Disease better than anything that the likelihood of agreement is considered a risk factor.
Sun power is a risk factor for the development of skin cancer, smoking is a tisk factor for
Development of lung cancer. primary risk factor in mesothelioma case
Is exposure to asbestos. Still, all this now before the sunlight or tobacco
Smoking is an asbestos cancer, holds true for the exhibition.

Asbestos, silicate fibers that environment, a group name are found naturally,
Period of several decades, large-scale industrial use in a range of 8 products were in
A million Americans at any time in my life from me before what may have been. Adjusting
Environmental (EPA) Agency, 733,000 schools and other public buildings protected
America still has asbestos insulation, and while most uses of asbestos have been now
Banned, there still are market products containing asbestos.

By the late 1800s asbestos used commercially, however, was enough use
During World War II era warships at shipyards have increased construction was completely
Curve. Even today, statistics show that the highest number of malignant mesothelioma cases
Coastal areas where shipyards were in operation in the set. Other risk business
Including construction workers, factory workers (especially those who install insulation),
Railway workers and employees and met. It was reported that family members
Because of increased risk for developing mesothelioma expressed are secondary workers
The work clothes, hair or fur fiber brought home show
With or around asbestos products. They finally diagnosed with mesothelioma, it can
Symptoms 20 or more years 50 started, and I do not think the risk
B with time - this is life.

The vast majority of mesotheliomas diagnosed for asbestos exposure are linked to where, there
Of Hodgkin's disease patients with history of agreement sometimes report
Their radioactive treatment of mesothelioma as a result. In these cases, mesothelioma developed
After an average treatment is 15 years, and most are located in radiated areas.

Absolute and relative risk :

Absolute risk is likely that a person will contract a particular disease
Within a specified period of time. For example, when epidemiologists say the American people
mesothelioma, facial development 1:4000 chance that they define are completed
Risk, average (the average risk population groups or generally deals shows.
And a general overall effect can not be associated with
Individual. Different risk estimates for different groups of people. Military police
60 last year in the development of mesothelioma small face greater risk
Man.

Relative risk compared to two different groups, with a group face a particular risk factor
While another group is not facing a specific threat. For example, researchers can
Those two groups as two groups with education part of joint facilities,
Age and socioeconomic profile. However, people who are a group of specific factors
Such as asbestos exposure. Researchers seek to determine the number of people
Each group a specific period of time may develop cancer. If twice as many
Invisible light as mesothelioma group is ready for a group of people, if
Members of the group of 2.0 showed a relative risk will be asked.

Both absolute and relative risk numbers can help tell the story is about a person
Mouth disease and the opportunity to contract mesothelioma diagnosis can be useful in
absolue risk of mesothelioma is lower for all groups. However, repeated studies
Shows that high asbestos fibers, mesothelioma relative risk of those exposed are the
Which have been shown.

SV40 conflict :

Over the years, some research studies indicating possible links between
SV40 (Simian virus) and risk of development of mesothelioma. Based on the idea
Injected polio vaccines prepared between 1955 and 1963 were contaminated with
Virus, it is estimated that 30 million people is 10 may appear.

Initial tests with laboratory animals, researchers found that infection with deliberately
SV40 mesotheliomas way to develop cancer and that asbestos can increase -
Effect of SV40 on these cells. Other researchers studying human biopsy samples
mesotheliomas SV40 DNA too, was found, however, found that SV40 DNA was
In non-cancerous tissue, they think that the virus was the main contaminants.

Both tissue and mesothelioma patients and healthy individuals was not there to study after
Obviously appear to be contaminants, SV40 virus has been linked mesothelioma when
Man was also highlighted asbestos. This research determined that SV40 infection
Polio vaccine was not due, but naturally other types of virus is
Infection.

Largest study of human history found no increased risk of mesothelioma in
Those who receive the vaccine as children, however, some researchers believe that
Many of the articles yet for the development of mesothelioma peak age was not reached . And research continues ...

Careful diagnosis of mesothelioma medical determination is obtained
Radiological and a book obtained from the biopsy. (Information about normal
Mesothelioma symptoms) the patient's history includes a review of medical history,
Having exposure to asbestos, is after a complete physical examination, chest radiography
Or the stomach, and lung function tests. A CT scan or an MRI this time what happens. If
These initial tests show suspected of mesothelioma), a biopsy is needed to confirm the
diagnosis.


Imaging techniques in the diagnosis:

Many of the imaging technology that is useful when the deadly mesothelioma can
The presence of pleural effusion from work or are suspected to date
secondary asbestos exposure. Although this imaging technique may be important to determine
Possibility of cancer, definitive diagnosis established more for now
Water or tissue biopsy diagnosis.

Imaging procedures:

• X Ray

Pleural effusion in chest X-ray screen (accumulation of water) can be imprisoned
OK (60%) or left (40%) of the lung. This time you can see a large scale. Signs of
first non - lung pleural plaques asbestos illness such as calcification or scarring
asbestosis may also be due.

• Computed tomography (CT)

Pleural effusion and CT scan are able to define pleural thickening, pleural
calcification, interlobular fissures, or a possible attack thickening of the chest wall. CT,
However, is not susceptible to changes associated with the difference between benign asbestos
Disease (lung disease) or lung adenocarcinoma that can distinguish between
It spread to the signs of pleural mesothelioma. TC can also be important in guiding fine
Tissue for diagnosis of pleural puncture of the people.

• Magnetic resonance imaging (MRI)

RM often aggressive tumor border is determined before
Treatment. They provide images in multiple planes, which may point to better
As a tumor against the normal structures. They are also right in TC
mediastinal lymph nodes according to their estimates (which is among the lymph nodes
The two lungs), therefore a clear diaphragmatic surface, which play a key role
Surgical role in this initiative.

• Positron Emission Tomography (PET)

The PET image evaluation and assessment is now becoming an important part of
mesothelioma. PET scan, while other types are more expensive and not
Provided under the insurance, now diagnose the tumor is considered the most
Sites, and staging of mesothelioma to determine the highest.

• CT / PET

That aggressive multimodal treatment of patients (candidates for surgery can be for
Chemotherapy and radiation), medically accurate staging is very important. Integrated
CT / PET in this sense is a relatively new tool, and is the image
To determine eligibility for the selection of surgical method. By combining the benefits of CT
And a PET (metabolic and anatomical information) scan, this technology can do more
Accurately determine the stage of cancer, and help identify the best treatment may
Option for the patient.

A needle biopsy of a large scale, or the removal and examination of water around
Lungs, can be used for diagnosis, however, because these samples are sometimes inadequate
However, the cell type (epithelial, sarcomatous, or mixed) or to determine the cause of
Assessment of water, open lung biopsy may be recommended unreliability. Lung in a
biopsy procedures, including a surgeon and the chest wall through a small incision will be a
clear, thin tube into the chest between two ribs called a thoracoscope. After that
to extract a sample of tissue under a microscope by a pathologist for review. One
peritoneal biopsy, the doctor inserts a stomach and a small incision
In peritoneoscope abdominal cavity.

Once mesothelioma is suspected through imaging tests, confirmed this condition
Test. Tissue is removed, is placed under the microscope, and makes a pathologist
The final diagnosis and a report on the problems of pathology. This is a process that is the end
The symptoms usually go to the doctor to send most people start with: an accumulation of fluid or
Pleural effusions, shortness of breath, chest pain, or pain or swelling in
Stomach. The doctor orders an X-ray or CT scan of the chest or abdomen can. If more
justifies the examination, you can try:

Video-assisted thoracoscopic surgery (VATS)

During the last decade, with the support of breastfeeding video (VATS) surgery has become one of use
mesothelioma diagnosis of the most widely used. The lining of the lung biopsy,
nodules, masses and pleural fluid readily available can now be attacked by at least
Process, and other treatments, such as pleurodesis (powder) for pleural effusion may be
concurrently.While patient is under general anesthesia, small incisions
"Port" through the thoracic wall. For a surgeon inserts a tiny camera time
Capacity is no incision, tissue samples and other surgical instruments used to obtain
In the characteristics of the other cuts. Watching a video screen showing images of camera type
Cree the method is able to meet the needs

In many cases, with the help of this video technology is capable of changing the thoracotomy, which
requires a large incision to access the thoracic cavity and at least this is because
Aggressive and more often in the patient's pain after surgery and a potentially less
Recovery period.

Thoracoscopy
 Pleural mesothelioma in the chest cavity with a private physician may feel
Instrument called a thoracoscope. A cut through the chest wall and
thoracoscope into the chest between two ribs will be. This test is usually used in a
Snuydnahary or pain to a local hospital.

If water is stored in the chest, the doctor of the water body by water can
A shot in the chest and gentle suction is used to remove water. It is said that
thoracentesis.

Peritoneoscopy

peritoneal mesothelioma doctor for a specific device can see inside the abdomen
A peritoneoscope met. peritoneoscope to open a branch in the stomach is made. This
A test usually done in hospital under local snuydnahary.

If water is stored in the stomach, the doctor of the water body for water can
Looking for a needle in the stomach and use gentle suction to remove water. This
Process is called paracentesis.

Biopsy

If abnormal tissue is found, doctors have a small piece and the need is
I hope under the microscope. This is usually done during the thoracoscopy or
peritoneoscopy, but can be done during surgery.

Role of Pathology in the evaluation process:

Pathology, or cell, tissue or fluid taken from a body of scientific studies
Important part of a diagnosis of mesothelioma. Most hospitals have their pathology laboratories
Board certified pathologists and licensed by the technology staff. Importance
pathological diagnosis can not be caused during the treatment without light depends
In an accurate diagnosis.

For diagnosis, pathologists examine the tissue under a microscope, and based on
Establish rules for resolving cells.Subsequently benign vs. malignant
Type of cancer is determined. Although the most common practice of pathologists is
Different diseases, a small number of mesothelioma, such as training in a subspecialty. This
Physicians and experts is in the world have recognized and received
More praise for his research, published articles and abstracts, and education. For a list
expert pathologists in the diagnosis of mesothelioma, please call toll-free MW
At 1-877-367-6376 or specify your request at the bottom of the page fill out the form.

Learn medical forum treatment plan to help form an important element. Mesothelioma is a
Considered local if the cancer is confined to the pleura, or if it has spread advanced
lungs, pleura outside, the wall of the chest, abdomen and other body parts
Cavity, or lymph nodes.

Immunohistochemical markers for mesothelioma


A special kind of cancer diagnosis often means ruling out other cancer in the
Process. This is true in the case of mesothelioma, where the most common difference "
Diagnosis is "To the adenocarcinoma mesothelioma.

During the process of biopsy tissue samples sent to the surgeon to remove
Laboratory. Lab and then saw production slide by a pathologist is analyzed.
The tissue samples in the laboratory with an application form details of the patient come
Body with the website information and date specified that Sample was obtained. Sample

number for each individual patient is all.

Pathologist a "total test" contains the description of tissue, and
Put it in a plastic cassette. Cassettes that are placed in a fixative
Permanently stored on paper. Once tissue has been fixed, it is implemented in
microscopic thin sections paraffin block which will allow the pathologist to cut off
To determine if the patient's diagnosis will stain.

Immunohistochemistry as "to analyze and identify types of cells based on a method specified
Cell "antibodies bind to specific parts. It is this process that
Mesothelioma diagnosis versus adenocarcinoma (cancer or other types) helps.

Skin, the "markers" which help distinguish mesothelioma from adenocarcinoma were
"Negative marker", but not in mesotheliomas those expressed in adenocarcinomas. It
This diagnosis more difficult, because pathologists to confirm the absence of combat was
, But the presence of some marker. Some of these markers, which are usually
Adenocarcinoma diagnosed in a "positive" and "negative" in a mesothelioma diagnosis, are
carcinoembryonic (CEA) antigen, CD 15 (LeuM1), epithelial glycoprotein (Bg8), tumor
glycoprotein (BerEp4) and tumor glycoprotein (MOC 31).

In more recent years, "positive marker" mesotheliomas come from display
Forefront. Markers, some of which are usually in mesotheliomas "positive" and "negative"
I adenocarcincomas calretinin, 5 cytokeratin, HBME - 1, mesothelin, cadherin (N) are,
thrombomodulin vimentin, and Wilm's tumor gene product (WT - 1). 2009 International
Mesothelioma Interest Group (mesothelioma doctors specializing in a collection) (explain)
"Pathologic diagnosis of malignant mesothelioma for directions."

It is important to remember that above marker detection usually is used to help
Subtype of epithelial mesothelioma, also other types that can be expressed in
Cancer, and necessary sub bị phasic or sarcomatoid type can not be applied to
mesothelioma. Your doctor always contact the lab a more specific if you can feel its
Evaluation couldn't find result.